KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.005 | - |
H2 | - |
Methanosarcina barkeri |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
integral to membrane | - |
Methanosarcina barkeri | - |
- |
membrane | - |
Pyrococcus furiosus | 16020 | - |
membrane | - |
Caldanaerobacter subterraneus subsp. tengcongensis | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe | contains [4Fe-4S] clusters | Methanosarcina barkeri | |
Fe | NiFe hydrogenase | Pyrococcus furiosus | |
Ni | contains NiFe centers | Methanosarcina barkeri | |
Ni | NiFe hydrogenase | Pyrococcus furiosus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
H+ + reduced ferredoxin | Pyrococcus furiosus | Mbh function as a redox-driven ion pump coupling the reduction of protons with electrons derived from the oxidation of a low-potential ferredoxin to the generation of a H+ motive force | H2 + oxidized ferredoxin | - |
? | |
H+ + reduced ferredoxin | Caldanaerobacter subterraneus subsp. tengcongensis | reaction is proposed to be coupled to energy conservation | H2 + oxidized ferredoxin | - |
? | |
H2 + oxidized ferredoxin | Methanosarcina barkeri | enzyme is absolutely required for the reduction of CO2 to formylmethanofuran by H2, Ech hydrogenase provides the cell with reduced ferredoxin required as electron donor | reduced ferredoxin + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caldanaerobacter subterraneus subsp. tengcongensis | - |
- |
- |
Methanosarcina barkeri | - |
- |
- |
Pyrococcus furiosus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
H+ + reduced ferredoxin | - |
Pyrococcus furiosus | H2 + oxidized ferredoxin | - |
? | |
H+ + reduced ferredoxin | - |
Caldanaerobacter subterraneus subsp. tengcongensis | H2 + oxidized ferredoxin | - |
? | |
H+ + reduced ferredoxin | Mbh function as a redox-driven ion pump coupling the reduction of protons with electrons derived from the oxidation of a low-potential ferredoxin to the generation of a H+ motive force | Pyrococcus furiosus | H2 + oxidized ferredoxin | - |
? | |
H+ + reduced ferredoxin | reaction is proposed to be coupled to energy conservation | Caldanaerobacter subterraneus subsp. tengcongensis | H2 + oxidized ferredoxin | - |
? | |
H+ + reduced methyl viologen | - |
Pyrococcus furiosus | H2 + oxidized methyl viologen | - |
? | |
H2 + oxidized ferredoxin | - |
Methanosarcina barkeri | reduced ferredoxin + H+ | - |
? | |
H2 + oxidized ferredoxin | enzyme is absolutely required for the reduction of CO2 to formylmethanofuran by H2, Ech hydrogenase provides the cell with reduced ferredoxin required as electron donor | Methanosarcina barkeri | reduced ferredoxin + H+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
hexamer | - |
Methanosarcina barkeri |
Synonyms | Comment | Organism |
---|---|---|
Ech hydrogenase | - |
Methanosarcina barkeri |
Mbh | - |
Pyrococcus furiosus |
membrane bound NiFe hydrogenase | - |
Pyrococcus furiosus |